Methods to identify epithelial stem cells

Epithelial tissue is a type that mainly covers the surfaces of body and organs. Most epithelial tissues are composed highly proliferative cells, necessitating robust stem cell activity. also most common site cancers. Therefore, identifying cells their self-renewal mechanisms prerequisite for promoting homeostasis, understanding cancer pathogenesis, developing regenerative therapy prevention. Over decades, diverse experimental techniques have been developed to identify in many organs from different angles. This review briefly introduces various methods used identification, rationales, examples applying those tools identification.